Après avoir été traité via TMF, une patiente n’a jamais eu de récidive d’épilepsie pendant les 20 mois de suivi et est resté sans crise sans médicaments antiépileptiques jusqu’à la date de cette soumission. Surtout, un enfant de sexe masculin est né par accouchement vaginal spontané normal avant cette approbation finale pour cet article. Par conséquent, il n’y avait pas besoin d’EEG pendant le suivi.
Fecal microbiota transplantation cured epilepsy in a case with Crohn’s disease: The first report
Fecal microbiota transplantation (FMT) is a promising strategy that involves reconstruction of gut microbiota. Recently, it has been considered as a treatment of Crohn’s disease (CD) and certain neurological diseases. Here, to the best of our knowledge, we report the first case that used FMT to achieve remission of intestinal and neurological symptoms in a girl with CD and a 17-year history of epilepsy. During the 20 mo of follow-up, FMT has proved its efficacy in preventing relapse of seizures after withdrawing the antiepileptic drugs. Furthermore, this finding highlights the role of microbiota-gut-brain axis and inspires a novel treatment for epilepsy through remodeling gut microbiota.
